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Biological Sciences Program

The Biological Sciences (BS) Program is designed for researchers and professionals with interests in the biological processes that underlie aging. Symposia and poster sessions will address the aging process at the molecular, cellular, and organismal level, as well as the specific disease conditions that are related to, or that accompany, the aging process.  Organized by the GSA Biological Sciences Section.

Biological Sciences Minority Investigator Travel Awards
Minority Investigator Travel Awards for students and post docs are available to support attendance at the 2019 Annual Scientific Meeting by individuals from groups underrepresented in biomedical research. This year, the Biological Sciences Section will award up to 8 travel awards in the amount of $1000 each for qualified attendees.

To be considered for the travel award, you must answer YES to the following question on the authors task of the abstract submission, “Is the author an individual from an underrepresented population in the biomedical, clinical, behavioral and social science as defined by the National Institutes of Health, Diversity in Extramural Programs”. Abstract submissions are due March 14. 
Experience five days of learning and training that include:

2019 Biological Sciences Program

Wednesday, November 13

8 am to 12 pm • Registration required
Pre-Conference Workshop
One Health for Healthy Aging: Companion Animals in Geroscience

12:30 to 2 pm
Expanding the Network: Non-Traditional Organismal Models in Geroscience

  • Marmosets as a Model for Aging and Age-Related Disease, Suzette Tardif
  • Genome-wide Relaxation of Selective Constraints Characterizes Evolution of Short Life Span in African Killifishes, Dario RiccardoValenzano
  • Longevity Mechanisms in Long-Lived Mammals, Vera Gorbunova
  • Conservation of Integrative Physiological Aging Mechanisms Across Primates, Alan Cohen

2:30 to 4 pm
Genomic Regulation of Aging

  • Genetic Dissection of Longevity, Rachel Brem
  • Sex-Dimorphic Mechanisms in Aging Innate Immunity, Berenice Benayoun
  • Understanding Genomic Regulation of Aging in Terms of Physiological States, Alex Mendenhall

4:30 to 6 pm
Nodes and Edges: Probing the Complex Interactions Between Diet, Disease and Aging

  • Caloric Restriction - Mechanisms at the Intersection of Nutrition, Health, and Aging, Roz Anderson
  • Nutritional Geometry: The Relationship Between Diet Composition and Lifespan in Mice, Samantha Solon-Biet
  • Novel Methionine-Related Pharmacological Interventions that Confer Healthspan Benefits to Budding Yeast and Rodents, Jay Johnson

6 to 8 pm
President's Welcome Reception and Exhibit Hall Opening
BS Poster Session (Face-to-Face Time with Presenters 6 to 7 pm)

Thursday, November 14

8 to 9:30 am
Immunity and Aging – The Human Face
Chair: Graham Pawalec

  • Dynamics of Memory CD8+ T Cells Across Human Life-Span and Tissue Compartments, Katherine Kedzierska
  • The Aging Microenvironment Drives an Emergence from Disseminated Melanoma Cell Dormancy, Mitchell Fane
  • Dysregulation of Innate Immunity in Aging, Ruth Montgomery

10  to 11:30 am
President’s Opening Plenary Session

12 to 1:30 pm
Biological Sciences Presidential Symposium: Expanding the Geroscience Network
Chair:
Matt Kaeberlein

  • Omics in Aging Research: From Biomarkers to Systems Biology, Daniel Promislow
  • Three-Dimensional Human Facial Morphologies as Robust Aging Markers, Jing-dong (Jackie) Han
  • Epigenetic and metabolic regulation of aging, Anne Brunet

2 to 3 pm
Poster Session II

3:30 to 5 pm
Targeting the mTOR Network to Maximize Healthspan

  • The Role of mTOR in Cell Senescence, Viviana Perez
  • Mechanisms of Neuroprotection from mTOR Inhibitors, Veronica Galvan
  • Sex and Tissue Specific Roles of mTORC2 in Healthspan, Metabolism and Survival, Dudley Lamming

5:30 to 7 pm
Is Aging an Acquired Mitochondrial Disease?

  • Mitochondria as Reversible Regulator of Skin Wrinkles and Hair Loss in Mice, Keshav Singh
  • Hypoxia as a Therapy for Age-Associated Mitochondrial Dysfunction, Isha Jain
  • Aging and Mitochondrial Disease: Shared Mechanisms and Therapies, Alessandro Bitto

Friday, November 15

8 to 9:30 am
Mechanisms of Cognitive and Neurological Aging

  • Mechanisms of Brain Rejuvenation, Saul Villeda
  • Jump Around Jump Around: Transposable Element Activation in Brain Aging and Neurodegenerative Tauopathy, Bess Frost
  • Harnessing Mouse Genetics to Identify Novel Therapies to Promote Resilience to Cognitive Aging and Alzheimer’s, Catherine Kaczorowski

11:30 am to 1 pm
BS Section Business Meeting and Award Presentation
separate registration required

1:30 to 2:30 pm
Poster Session III

3  to 5:30 pm
Intervening in the Longevity Network

  • An FDA Approved Compound that Increases Lifespan Through a Novel Mechanism, Mark McCormick
  • Targeting Kynurenine Metabolism in Age-Associated Disease, George Sutphin
  • Drug Synergy Slows Aging and Improves Healthspan, Jan Gruber

6 to 8 pm
Irving S. Wright and Vincent Cristofalo “Rising Star” Award Presentation, Lecture, and Reception
These awards are given by American Federation for Aging Research (AFAR) Inc.

Saturday, November 16

8 to 9:30 am
ESPO/ Biological Sciences Section Symposium: The Crossroads of Aging—Targeting Immunity, Metabolism, and Cellular Stress
Chair:
Matt Kaeberlein, Jessica Hoffman

11:30 am to 1 pm
Kent and Kleemeier Award Lectures

1:30 to 2:30 pm
Poster Session IV

1:15 to 2:45 pm
Cell Non-Autonomous Mechanisms of Aging

  • Cell Non-Autonomous Serotonin Signaling Mediates Stress Resistance and Longevity, Scott Leiser
  • Neuronal FGF-21 Signaling: A Sensor of Dietary Protein, Cristal Hill
  • Increased HSP25 in Peripheral Tissue Protects Against Neural Tauopathy, Karl Rodriguez

3 to 4:30 pm
Fondation IPSEN Longevity Prize Award Lecture

5 to 6:30 pm
Systems biology of aging

  • Systems Level Understanding of Aging, Slava Labunskyy
  • Measuring and Modeling Competing Risks of Death During Aging, Nicholas Stroustrup
  • Systems Biology of Single-Cell Aging - Programmed Fate Bifurcation During Cellular Aging, Nan Hao

Sunday, November 18

9 to 11:30 am
Clinical interventions in geroscience:

This session will focus on clinical trials that are testing interventions developed from basic research on the biology of aging.  It will feature scientists at the cutting edge of clinical interventions in geroscience. Each speaker will give a short report followed by a roundtable discussion.

Confirmed Participants:

Brian Kennedy
Joan Mannick
Jamie Justice

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