Clinical Trials and Older Adults

Clinical Trials and Older Adults — Strategies to Drive Older Adult Participation

Momentum Discussion at GSA's 2018 Annual Scientific Meeting
Moderator: Stephanie A. Studenski
Panelists: Roger A. Fielding, Jay S. Magaziner

Individuals enrolled in a clinical trial of a novel intervention ought to represent those who are intended to benefit. However, older adults, especially those with multimorbidity or frailty, are under-represented in most trials, even when they may benefit and are likely to use the intervention in real life. While practical barriers and unnecessary research assumptions have limited participation, multiple feasible solutions exist. This session, based on a recent conference, described the strengths and limitations of trial design and implementation strategies that can open the door to greater participation by, and generalizability to, a broad range of older adults.

Recruiting Older Adults for Clinical Trials: Communication Tips for Clinical Investigators

Vignette (link coming soon)
Until recently, older adults were generally not well-represented in clinical trials. As a result, the evidence base for guiding treatment in this population is less robust than for younger adults. Efforts are underway to ensure that more diverse patient populations are included in clinical trials. Therefore, enrolling older adults in clinical trials is important for supporting these efforts. Increasing communication with older adults about clinical trials is likely to improve enrollment. In fact, more than two-thirds of Americans say it’s likely they would participate in a clinical trial if recommended by their doctor. In this video, we will review tips for communicating with older adults, including both general communication strategies and specific points for discussing clinical trial enrollment.

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